Description
Convert your existing benchtop glass bioreactor to a single-use bioreactor in seconds!
The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds. Upon media addition, the liner expands and molds to the glass vessel, preserving the geometry of the existing bioreactor.
The BIOne SUB’s liner material emulates the large-scale SUBs used in pilot and commercial biopharma production facilities around the world. Performing R & D studies using the most similar material on the market streamlines your tech transfer and can de-risk your process BEFORE transferring to pilot scale.
Features:
Customizable Above & Below The Headplate
- 2L, 5L, & 10L Working Volume
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Optional Single-Use pH Probe
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Increased Throughput
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Weldable Tubing
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Flute, Micro & Open Pipe Sparging Options
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Non-Invasive DO & Optional pH Probe Ports
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USP Class VI Materials
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Repligen® ATF Perfusion Tube Compatible
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Animal Derivative-Free
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Low Antioxidant Liner Material
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Compatible with Most Manufacturers’ Glass Vessels and Controllers
DO & pH Probe Ports
- Non-Invasive (Amperometric DO/Optical pH)
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PG-13.5 (Optical DO/Electrochemical pH)
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Optional Integrated Single-Use pH Probe
Pitched Blade Impeller
Sparging Options
- Flute Sparger (7 x 1.5 mm hole)
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Micro Sparger (20-40 µm pore size)
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Open Pipe Sparger (1 x 3.0 mm)
Low Antioxidant Liner Materia
- Outer Layer (LDPE) – Mechanical Strength
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Middle Barrier Layer (EVOH) – Gas Barrier
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Contact Layer (ULDPE) – Cell Culture Compatible, Biologically Inert